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CRACOVIA-HF

UMED as a Consortium member/ Partner

Project name: CRACOVIA-HF

Project title: A multicenter, randomized, double-blind, active-controlled study to evaluate the influence of sacubitril/valsartan compared to ramipril on left ventricular function and remodeling in patients with ischemic heart failure with mid-range ejection fraction

Project name: TreatWolfram

Project title: An international, randomized, double-blinded, pivotal clinical trial with the aim to evaluate the efficacy and safety of sodium valproate in children and adults with Wolfram syndrome.

What the study is about: Wolfram syndrome

Project name: Interfant-21

Project title: International collaborative treatment protocol for infants under one year with KMT2A-rearranged acute lymphoblastic leukemia or mixed phenotype acute leukemia.

What the study is about: KMT2A-rearranged acute lymphoblastic leukemia or mixed phenotype acute leukemia in infants

Project name: EMPATHY

Project title: EMpagliflozin and daPAgliflozin in patients hospiTalized for acute decompensated Heart failure (EMPATHY trial)

What the study is about: acute heart failure (AHF)

Project name: Protect ICD

Project title: Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction.

What the study is about: poor heart function after myocardial infarction (MI)

Project name: Forma

Project title: FORMA – a multicentre randomized-controlled trial to evaluate the efficacy and safety of ketoanalogues of essential amino acids in prophylaxis of protein-energy wasting in nephrotic syndrome.

What the study is about: eating disorders, nephrotic syndrome (NS)

Project name: RemiRit

Project title: RemiRit - Personalized immunosuppressive therapy with rituximab in the treatment of ANCA associated vasculitis - a randomized, multicenter clinical trial.

What the study is about: systemic vasculitis with the presence of ANCA antibodies

Project name: RaRE-TS

Project title: Multicenter, randomized, double-blind, placebocontrolledstudy to assess the efficacy and safety of Rapamycin in drug Resistant Epilepsy associated with TSC (RaRE-TS).

What the study is about: epilepsy, tuberous sclerosis

Project name: RATIONAL

Project title: A phase II efficacy and safety study of cell-free circulating tumor DNA-guided commencement of second-line treatment in patients with DLBCL/HGBCL relapse.

What the study is about: DLBCL / HGBCL lymphoma

Project name: Car-NET

Project title: Polish Chimeric Antigen Receptor T-cell Network

Project name: ViRap

Project title: Randomized, placebo-controlled, double-blind and double-dummy clinical trial comparing the safety, tolerability, and efficacy of vigabatrin and rapamycin in a preventive treatment of infants with Tuberous Sclerosis Complex (ViRap).

What the study is about: epilepsy, mental retardation, autism, tuberous sclerosis

Project name: LEIA-HF

Project title: LEIA-HF: Levosimendan In Ambulatory Heart Failure Patients

What the study is about: ciężka niewydolność serca (NS)

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