Our Projects
Project name: PICOLO-FH trial
Project title: ComParison of InClisiran Or aLirOcumab to standard therapy in pediatric Familial Hypercholesterolemia – the head-to-head PICOLO-FH clinical trial
Project name: BOOSTER trial
Project title: B cell depletion therapy to improve outcomes of steroid-sensitive nephrotic syndrome in adults – the BOOSTER trial
What the study is about: idiopathic steroid-sensitive nephrotic syndrome (SSNS)
Project name: COMBO-UC trial
Project title: Comparison of ustekinumab, infliximab and COMBinatiOn therapy in moderately-to-severely active Ulcerative Colitis – the head to head COMBO-UC trial
What the study is about: Ulcerative colitis
Project name: cALL-POL
Project title: Childhood ALL in Poland (cALL-POL) project: a national harmonization of diagnostics and treatment of acute lymphoblastic leukemia in children
What the study is about: acute lymphoblastic leukemia (ALL)
Project name: MAGIC-AML
Project title: MAGIC-AML - Multiarm, Multicenter, RAndomized, Molecularly-GuIded Controlled Trial of Personalized Treatment Strategy - of Acute Myeloid Leukemia
What the study is about: AML, acute myeloid leukemia (AML)
Project name: LAMAinDiab
Project title: LAMAinDiab – lisdexamphetamine vs metylphenidate for pediatric patients with attention-deficit hyperactivity disorder and type 1 diabetes – randomized cross-over clinical trial
What the study is about: ADHD, type 1 diabetes
Project name: Alzheimer
Project title: Randomized, double-blind, placebo-controlled trial evaluating efficacy and safety of dimethyl fumarate in brain atrophy reduction, synaptic functional connectivity, cognitive functions, quality of life, and activity of daily living improvement among patients with mild cognitive impairment and dementia due to Alzheimer’s disease.
What the study is about: Alzheimer
Project name: STEADY
Project title: Prospective, randomized, open-label Phase III clinical trial with blinded endpoint assessing the efficacy and safety of ciclosporin and methotrexate in children and adolescents with moderate to severe atopic dermatitis.
What the study is about: Atopic dermatitis (AD)
Project name: LEIA-HF
Project title: LEIA-HF: Levosimendan In Ambulatory Heart Failure Patients
What the study is about: ciężka niewydolność serca (NS)
Project name: ViRap
Project title: Randomized, placebo-controlled, double-blind and double-dummy clinical trial comparing the safety, tolerability, and efficacy of vigabatrin and rapamycin in a preventive treatment of infants with Tuberous Sclerosis Complex (ViRap).
What the study is about: epilepsy, mental retardation, autism, tuberous sclerosis
Project name: Car-NET
Project title: Polish Chimeric Antigen Receptor T-cell Network
Project name: RATIONAL
Project title: A phase II efficacy and safety study of cell-free circulating tumor DNA-guided commencement of second-line treatment in patients with DLBCL/HGBCL relapse.
What the study is about: DLBCL / HGBCL lymphoma
Project name: RaRE-TS
Project title: Multicenter, randomized, double-blind, placebocontrolledstudy to assess the efficacy and safety of Rapamycin in drug Resistant Epilepsy associated with TSC (RaRE-TS).
What the study is about: epilepsy, tuberous sclerosis
Project name: RemiRit
Project title: RemiRit - Personalized immunosuppressive therapy with rituximab in the treatment of ANCA associated vasculitis - a randomized, multicenter clinical trial.
What the study is about: systemic vasculitis with the presence of ANCA antibodies
Project name: Forma
Project title: FORMA – a multicentre randomized-controlled trial to evaluate the efficacy and safety of ketoanalogues of essential amino acids in prophylaxis of protein-energy wasting in nephrotic syndrome.
What the study is about: eating disorders, nephrotic syndrome (NS)
Project name: Interfant-21
Project title: International collaborative treatment protocol for infants under one year with KMT2A-rearranged acute lymphoblastic leukemia or mixed phenotype acute leukemia.
What the study is about: KMT2A-rearranged acute lymphoblastic leukemia or mixed phenotype acute leukemia in infants
Project name: TreatWolfram
Project title: An international, randomized, double-blinded, pivotal clinical trial with the aim to evaluate the efficacy and safety of sodium valproate in children and adults with Wolfram syndrome.
What the study is about: Wolfram syndrome
Project name: EMPATHY
Project title: EMpagliflozin and daPAgliflozin in patients hospiTalized for acute decompensated Heart failure (EMPATHY trial)
What the study is about: acute heart failure (AHF)
Project name: Protect ICD
Project title: Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction.
What the study is about: poor heart function after myocardial infarction (MI)
Project name: FlexiOss
Project title: Safety and efficacy of implanted bio-composite for bone regeneration FlexiOss in patients with primary and secondary bone defects.
What the study is about: bone defects