RaRE-TS

Project title: Multicenter, randomized, double-blind, placebocontrolledstudy to assess the efficacy and safety of Rapamycin in drug Resistant Epilepsy associated with TSC (RaRE-TS).

Project data

Project financing: 16 880 726,88 PLN (including financing for UMED: 3 611 233,02 PLN), financed by the Medical Research Agency (ABM)

Project description:

The aim of the project is to evaluate the efficacy, tolerability and safety of rapamycin as add-on therapy to antiepileptic drugs in patients with drug-resistant epilepsy associated with tuberous sclerosis. In addition, the RaRE-TS study will prospectively analyse molecular, electrophysiological and neuroimaging biomarkers of epileptogenesis and oncogenesis.

The project is being carried out in a consortium with the Institute – Pomnik “Children’s Health Centre” as leader and Medical University of Lodz as partner.

Beneficiary

Consortium composed of:

Institute “Children’s Health Centre Memorial” (Leader)

Medical University of Lodz (Partner)

TRANSITION TECHNOLOGIES SCIENCE SP. Z O.O. (Partner)

Medical University of Warsaw (WUM) (Partner)

Brigham and Women’s Hospital (Partner)

Coordinating Principal Investigator

prof. Katarzyna Kotulska-Jóźwiak, MD, PhD

UMED Site Principal Investigator

prof. Wojciech Młynarski, MD, PhD

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