Rivals

PROJECT TITLE RIVALS study – evaluation of the efficacy of ofatumumab treatment in patients with refractory idiopathic inflammatory myopathies compared to subcutaneous immunoglobulins.

CRACOVIA-HF

Project title: A multicenter, randomized, double-blind, active-controlled study to evaluate the influence of sacubitril/valsartan compared to ramipril on left ventricular function and remodeling in patients with ischemic heart failure with mid-range ejection fraction

ViRap

Project title: Randomized, placebo-controlled, double-blind and double-dummy clinical trial comparing the safety, tolerability, and efficacy of vigabatrin and rapamycin in a preventive treatment of infants with Tuberous Sclerosis Complex (ViRap).

RATIONAL

Project title: A phase II efficacy and safety study of cell-free circulating tumor DNA-guided commencement of second-line treatment in patients with DLBCL/HGBCL relapse.

RaRE-TS

Project title: Multicenter, randomized, double-blind, placebocontrolledstudy to assess the efficacy and safety of Rapamycin in drug Resistant Epilepsy associated with TSC (RaRE-TS).

RemiRit

Project title: RemiRit – Personalized immunosuppressive therapy with rituximab in the treatment of ANCA associated vasculitis – a randomized, multicenter clinical trial.

Forma

Project title: FORMA – a multicentre randomized-controlled trial to evaluate the efficacy and safety of ketoanalogues of essential amino acids in prophylaxis of protein-energy wasting in nephrotic syndrome.

Interfant-21

Project title: International collaborative treatment protocol for infants under one year with KMT2A-rearranged acute lymphoblastic leukemia or mixed phenotype acute leukemia.

TreatWolfram

Project title: An international, randomized, double-blinded, pivotal clinical trial with the aim to evaluate the efficacy and safety of sodium valproate in children and adults with Wolfram syndrome.

EMPATHY

Project title: EMpagliflozin and daPAgliflozin in patients hospiTalized for acute decompensated Heart failure (EMPATHY trial)